Lack of genic variation in the abundant proteins of human kidney.

نویسندگان

  • S C Smith
  • R R Racine
  • C H Langley
چکیده

Abundant proteins of 25 human kidneys were surveyed for genic variation by means of two-dimensional electrophoresis. Eighty-three (83) proteins were scored, and no genic variation was detected. This reduction in genic heterozygosity corroborates results determined with two-dimensional electrophoresis in mice and flies. These results suggest that previous estimates of electrophoretic variation may have been in error because of biased selection of loci.

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عنوان ژورنال:
  • Genetics

دوره 96 4  شماره 

صفحات  -

تاریخ انتشار 1980